A multimodal method of agony management might enhance the treatment of Serious ache, and aid With all the effective tapering in the opioid analgesic (see WARNINGS, Withdrawal and DRUG ABUSE AND DEPENDENCE).
Infants born to moms bodily depending on opioids will also be physically dependent and may show respiratory issues and withdrawal indicators (see Safeguards, Pregnancy).
e., several copies of your gene for cytochrome P450 isoenzyme 2D6 or large morphine concentrations). Youngsters with slumber apnea may be specifically delicate for the respiratory depressant effects of codeine. Due to the hazard of daily life-threatening respiratory depression and Demise:
When this medication is applied for many years, it may not get the job done as well. Talk to your medical doctor if this medication stops Functioning perfectly.
noticing your pain acquiring even worse. When your pain gets worse Once you take acetaminophen and codeine phosphate tablets, tend not to acquire extra of acetaminophen and codeine phosphate tablets with no to start with speaking to your healthcare supplier.
Drug interactions could alter how your prescription drugs perform or increase your possibility for really serious side effects. This doc will not include all probable drug interactions.
Go over The provision of naloxone for that unexpected emergency therapy of opioid overdose Using the affected person and caregiver and evaluate the possible need to have for use of naloxone, both equally when initiating and renewing procedure with acetaminophen and codeine phosphate tablets (see WARNINGS, Lifetime-Threatening Respiratory more info Depression; PRECAUTIONS, Information and facts for Individuals/Caregivers).
Breastfeeding just isn't proposed even though getting this drug; nursing mothers must be instructed to seek quick health care notice for infants encountering elevated sleepiness, trouble breastfeeding, breathing website difficulties, or limpness.
To lessen the chance of respiratory here depression, correct dosing and titration of acetaminophen and codeine phosphate tablets are essential (see DOSAGE AND ADMINISTRATION).
Abuse of more info and habit to opioids in a few folks might read more not be accompanied by concurrent tolerance and symptoms of physical dependence. On top of that, abuse of opioids can manifest during the absence of dependancy.
Viagra® and generic Viagra® may well influence how other medicines perform, and other medicines may well influence the way in which Viagra® and generic Viagra® works, causing side effects. Drug Interactions
Use with warning; start with decrease doses or with more time dosing intervals and titrate slowly though very carefully checking for Unwanted side effects.
Misuse and abuse of acetaminophen and codeine phosphate tablets will increase hazard of overdose, which may cause central anxious program and respiratory despair, hypotension, seizures, and death. The chance is increased with concurrent abuse of acetaminophen and codeine phosphate tablets with Liquor and various CNS depressants.
Make use of other supportive steps (including oxygen and vasopressors) inside the administration of circulatory shock and pulmonary edema as indicated. Cardiac arrest or major arrhythmias will require Innovative lifetime-aid actions.